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[platne_od] => 10.04.2017 16:05:00
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[zmeneno_uzivatel_jmeno] => Antonín Mareš
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Technická 5
166 28 Prague 6 – Dejvice
IČO: 60461373 / VAT: CZ60461373
Czech Post certified digital mail code: sp4j9ch
Copyright: UCT Prague 2017
Information provided by the Department of International Relations and the Department of R&D. Technical support by the Computing Centre.
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[obsah] => Deepening of cooperation in bioactive compounds research (BIOCOM)
The proposed project aims at deepening of cooperation in common research activities between two universities in Czech Republic and Norway, University of Chemistry and Technology, Prague (UCT Pragure) and UiT The Arctic University of Norway (UiT), respectively. Strengthening and improvement of activities in the field of biologically active compounds research is planned. The partners will benefit from sharing and transfer of complementary scientific competences. UiT team is highly recognized for its credit in the field of bioprospecting, i.e. discovery and commercialization of ´new´ products based on biological resources, specifically marine. For this purpose, advanced biotechnologies, including isolation and purification of bioactive compounds are being developed by UiT jointly with industrial partners. On the other hand, UCT Prague is known for the excellence in the field of advanced, comprehensive analysis of natural matrices, what is the field which UiT is going to develop to reduce the need of outsourcing analytical services. The experience in employing cutting edge instrumental platforms for both bioactive compounds identification and quality / safety / stability parameters control will be the UCT´s project input. Another area for close collaboration and generic knowledge transfer is bioactivity testing. UiT employs an array of biochemical and cellular tests that might be implemented at UTC that has recently bought a robotic platform for this purpose. Both young scientists (PhD students), and experienced academics and senior research staff will increase their research profiles and enhance the skills in interdisciplinary communication through series of short-term trainings / study stays, expert’s visits and participations in events organised by project partners. The cooperation will also enable establishing the new collaborative research teams which will follow the present research, and will also support future extension of the collaboration to include research projects focusing on exploitation of natural resources in general.
The project "Deepening of cooperation in bioactive compounds research" (BIOCOM) benefits from a 791 000 CZK grant from Norway Grants. The aim of the project is to stimulate long-term cooperation, networking, knowledge sharing and transfer, capacity and competence building in the research field focused on biologically active compounds.
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Project title:
Deepening of cooperation in bioactive compounds research
Project coordinator:
Prof. Jana Hajslova, Ph.D., UCT Prague
Total budget: 791 000 CZK
Project duration:
1 February 2017 – 30 April 2017
Project No: 7F16028
CZ09 - Czech-Norwegian Research Programme
NORWAY GRANTS
Through the Norway Grants and EEA Grants, Norway contributes to reducing social and economic disparities and to strengthening bilateral relations with the beneficiary countries in Europe. Norway cooperates closely with the EU through the Agreement on the European Economic Area (EEA).
For the period 2009-14, Norway’s contribution is €1.7 billion. Grants are available for NGOs, research and academic institutions, and the public and private sectors in the 12 newest EU member states, Greece, Portugal and Spain. There is broad cooperation with Norwegian entities, and activities may be implemented until 2016.
Key areas of support are environmental protection and climate change, research and scholarships, civil society, health and children, gender equality, justice and cultural heritage.
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Initiative 1
Activity 1
2 short-term trainings / study stays of PhD students from UCT Prague at UiT to gain the knowledge about (a) the marine resources as animals, bacteria, microalgae, plants etc. for use in bioprospecting, (b) suitability and application of different methods for the use in research related to bioprospecting, (c) bioavailability, bioactivity and potential toxicity assessment; (d) biotechnologies producing final product based on bioactive compounds
(i) Practical training in the UiT laboratory to get familiar with the strategies employed in bioprospecting research including sample handling, description, storage, prior- analysis processing, bioactivity and potential toxicity testing; up-scaling of laboratory practices into real-life biotechnology scale. More information here.
(ii) Participation in PhD training course (PhD Course BIO-8009: Marine bioprospecting and bioactive compounds for health) organised by UiT. More information here.
Activity 2
Short-term training / study stay of PhD students from UiT at UCT Prague
Practical training in the lab to gain knowledge on advanced analytical strategies based on employing ultra-performance liquid chromatography coupled to tandem high resolution mass spectrometry (UPLC-HRMS/MS) for identification of biologically active compounds in biological matrices. Optimization of analytical method, using various databases for compounds identification, chemometric data processing employing multi variate statistics
Activity 3
Experts´ visit of UCT Prague research staff at UiT
Academic staff from UCT Prague attending the Norwegian UiT will gain new experience leading to strengthening of bilateral relations; (i) will explore new opportunities for research collaboration, particularly possibilities for common project proposals in the field of food and biotechnology sciences, (ii) will plan common research activities leading to preparation of scientific paper(s). More information here.
Activity 4
UiT representative’s participation and presentation at the conference organised by UCT Prague
Prof. Stensvag will participate with keynote lecture on topic related to the project activities in the conference Chemical Reactions in Foods VIII (CRF 2017, www.crf2017.eu) organised by UCT Prague on 15-17 February 2016 in Prague. More information here.
Initiative 2
Organisation of a workshop on topic related to biologically active compounds in natural resources. More information here.
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The Faculty of Biosciences, Fisheries and Economics
Key people at NMBU
Klara Stensvåg, Professor
Dr. Klara Stensvåg is professor in Marine Biotechnology form The UiT The Arctic University of Norway, Tromsø. She took her PhD in 1998. Her main research focus is use of different marine bioresources and she has been working on fish immunology and defense molecules in marine invertebrates. The main activity in ongoing projects is marine bioprospecting and drug discovery with a particularly focus of antimicrobial compounds and bioactive peptides. She has been a member of a national scientific board in biotechnology and teach in Marine Biotechnology.
University of Chemistry and Technology, Prague (UCT)
Department of Food Analysis and Nutriton
Key people at UCT
Jana Hajslova, Professor
Prof Jana Hajslova is the head of the Department of Food Analysis and Nutrition, University of CHemistry and Technology, Prague (UCT Prague) and chairs Accredited (ISO17025) Laboratory "Food Quality and Safety". She is a widely recognized expert in the field of food / environmental chemistry and analysis; she has published more than 250 original papers on development of advanced analytical strategies of contaminants, residues, natural toxins and other biologically active compounds, authentication and metabolomics. Her research team has participated in many international and national projects at both research and management levels, including the EC 5 - 7th Framework Programme, HORIZON 2020, several COSTs and EEA and Norwegian grants. Prof Hajslova together with her PhD students has been involved in various bilateral international research activities; under her supervision, close collaboration with many world-renowned institutions, such as WHO, FAO, USDA and the European Commission’s Joint Research Centre has been established. Currently she is the Czech Republic delegate in HORIZON 2020 SOCIETAL CHALLENGE 2: "Food Security, Sustainable Agriculture and Forestry, Marine and maritime and inland water research and the Bioeconomy" committee. As the chairwomen, she had a key input in establishing a series of very reputable international symposia "Recent Advances in Food Analysis" series in 2003-2015.
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University of Chemistry and Technology, Prague (UCT Prague)
Department of Food Analysis and Nutrition
Technicka 3
Prague 6
16628
Czech Republic
Contact persons of the institution:
Martina Vlckova
e-mail: martina.vlckova@vscht.cz
Tel: +420220443180
The Arctic University of Norway, Tromso (UiT)
The Faculty of Biosciences, Fisheries and Economics
P.O. Box 6050 Langnes
Tromso
9037
Norway
Contact persons of the institution:
prof. Klara Stensvag, Ph.D.
mail: klara.stensvag@uit.no
Tel: +4777644512
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Name of trainees: Darina Lanková, Veronika Krtková, Monika Jírů, Marie Bícová
Home Institution: University of Chemistry and Technology (UCT) Prague
Faculty of Food and Biochemical Technology
Department of Food Analysis and Nutrition
Address of home institution: Technická 3, Prague 6 Dejvice, 166 28, Czech Republic
Name of supervisor in the home institution: Prof. Ing. Jana Hajšlová, CSc.
Visited project partner: UiT The Arctic University of Norway (UiT)
Address of project partner: UiT Norges arktiske universitet, Postboks 6050 Langnes, 9037 Tromsø
Name of supervisor in the project partner: Prof. Klara Stensvåg
Actual period of visit: April 3.-9. 2017
Short summary of training:
(In detail see attachment no. 1.)
Tuesday April 4
Tour around the laboratories at the Department of NFH, followed by the introduction to lab routines and tour in the laboratory facilities. Short introduction to Marine bioprospecting and methods of bioassay guided purification. Demonstration of bioactivity testing of antimicrobial activity.
Wednesday April 5
The talk about searching for antimicrobial active components in marine organism. Lectures: „Pyridine and piperidine; Privileged heterocycles in drug discovery“ and „Synthetic mimics of antimicrobial peptides - Synthesis and biological studies of novel synthetic mimics of antimicrobial peptides“
Thursday April 6
Antimicrobial peptides and cases form own research. Mechanisms of actions studies. Introduction for preparation for biosensoric assays and mode of actions studies of antimicrobial compounds. Supply issues of natural products. Practical session doing two biosensoric assays of mechanisms of actions of antimicrobial activity.
Friday April 7
Seminar with presentation of PhD projects.
Titles: Organohalogen contaminants in human environment (Darina Lanková)
Biological active compounds of Cannabis plant (Veronika Krtková)
Opium alkaloids in capsules and seeds of Poppy (Papaver somniferum L.) (Marie Bícová)
Food fraud of botanical-based dietary supplements (Monika Jírů)
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